The Experimental Medicine Training Initiative (EMI) is an exciting, new strategic scheme, supported by the University of Cambridge in partnership with the Cambridge University Hospitals, NIHR Cambridge Biomedical Research Centre and Industry Partners AstraZeneca/MedImmune and GSK, designed to build capacity in Experimental Medicine (EM).
The development of new drugs and innovative therapies increasingly relies on EM studies in humans, such as obtaining early proof-of-concept, understanding (patho-) physiology, biomarker development/validation, and evaluating techniques for subject stratification. Currently there is a lack of individuals trained to design and deliver such studies, which is impacting on drug development. Academia and pharmaceutical R&D are keen to collaborate to address this translational research gap, and in doing so deliver high quality Experimental Medicine projects.
Training will be customised to the needs and previous experience of individuals, and be open to clinicians at all career levels, and a small number of talented non-clinicians keen to work at the interface between pre-clinical and clinical science. The main emphasis will be on PhD studentships and post-doctoral fellows, the latter provided by the creation of EM Academic Clinical Lectureships (ACLs). There will also be opportunities for MPhils, more junior academic clinicians, and senior consultant level posts.
All trainees will have the opportunity for hands-on exposure to the design and conduct of EM studies investigating the therapeutic potential of new drugs in collaboration with our industrial partners. These will usually be early phase clinical trials designed to provide early proof of concept, to identify biomarkers or stratifiers of response; or be physiological studies to probe pathophysiology of diseases or toxicology. Projects are developed jointly between academic and pharmaceutical partners, and where possible trainees. For PhD students the project will form the centre-piece of their research, which may also involve more laboratory-centred research.
Trainees will have the option of spending time with an industrial partner to undertake research and/or obtain exposure to other aspects of EM to meet their personal training needs. Where appropriate, trainees may also join the taught component of the University of Cambridge’s MPhil in Clinical Sciences/EM, which will afford formal teaching in a wide range of translational and pharmacological areas such as drug development, pharmacokinetics, toxicology, and statistics. We will also equip trainees with the skills required to communicating research findings to academic and other audiences through academic publication and other routes.
Types of posts available
Information regarding PhD positions, Junior Medical Training and Clinical Lectureships can be found on this site. Details regarding Senior Experimental Medicine Investigators and Post-Doctoral Clinical Scientists Posts can be found on our website.
These will be 3 year posts, with an additional 6-month taught component for those who have not completed the MPhil, which will equip students with the scientific and regulatory knowledge required to undertake Experimental Medicine studies in man.
Students will cover the following modules from the new MPhil in Clinical Science and specialist training in Clinical Pharmacology: Practical Aspects of Clinical Research; Basic Pharmacology; Pharmacokinetics; Toxicology; Clinical Drug Development; and Medical Statistics.
PhD projects will be developed jointly by industry and academic partners, and should include at least one Experimental Medicine study involving giving a drug/or challenge agent to human subjects. Other components may include mechanistic, laboratory-based analyses, and biomarker discovery/development/validation.
There is an option to spend up to a year based with the industrial partner, or other Departments within the University. All students will have joint University and industry partner supervisors, and a separate academic mentor.
If you require any more information or wish to apply please follow the link: http://cato.medschl.cam.ac.uk/graduate-programmes/phd-programmes/experimental-medicine-training-initiative-emi/.